Are you mean't to mix Levemir & Humalog in one syringe?
I've got fed up with my Insulin Pump, especially in bed, when I can't sleep in the heat and getting tied up in the wire
I've got back to MDI for a bit, have been mixing the two in the morning and at night to save two injections.
Also, how long does levemir last? in your body I mean.
No you can't mix the two together, mixing the two makes them unstable and may make them less effective, something to do with the pH difference between the two insulin's.
I'll stop it now and have them seperate.
The following is potentially going to cause see confusion
but in a nut shell the jury is still out regarding whether
Levemir (Insulin Detemir) and
Humalog (Insulin Lispro) can be mixed together and injected.
Even health care professionals have been unable to come to an overall consensus on what to advise.
¡°If you are treated with
Levemir and another insulin/s you should
use a separate delivery device for each type of insulin injected.¡± (NovoNordisk 2005)
Levemir requires two injections a day but it
can be mixed in the same syringe with any of the rapid acting analogues.¡± (Walsh et al Using Insulin 2004 page 105)
With regard to the
7-7.8 therefore mixing it should make little difference.
Always draw up the rapid acting analogue first.
Some users have reported problems with the
Levemir slowing down the action of whatever it was mixed with.
The only insulin that is not advised for mixing with another insulin is
Lantus (Insulin Glargine) - pH 4 because of the different pH, and if you mix it with another insulin of a normal ph it will degrade faster.
There are several studies on mixing
Novorapid (Insulin Aspart)and interestingly the outcome was completely different in these two studies:
Levemir (Insulin Detemir) with
Novorapid (Insulin Aspart) resulted in a 40% reduction in the bioavailability and peak concentration of the latter agent.¡± Hussar 2006
Insulin detemir mixed with
aspart had equivalent effects on blood glucose versus giving them as separate injections." Nguyen 2010
Confusing isn¡¯t it
As to how long does
Levemir last ¨C that is really going to be determined by your own use of it and playing detective as to how long it lasts in you
Duration: Up to 18 hours (Coopen 2007)
18-22 hours (Diabetes Daily)
10-14 hours (Medscape)
Peaking action is considered to be 3-9 hours (although peaking action is not pronounced).
Hope the above might help.
Yeah, definitely wouldn't mix lantus as it basically crystallises under the skin in order to maintain a 24 hour action. How come it's so acidic though? No wonder so many people say it stings!
Thanks, all I can say is, glad i've put my pump back on!